Exclzyme vs Vitalzym Brand Comparison

There are several systemic enzyme brands available in today’s health-conscious market. How do you know which brand is the right one for you? Understanding the quality and origin of your enzyme supplement is a critical component in this decision.

A major difference between AST and competing brands is that AST Enzymes is a true manufacturer. Many systemic enzyme brands are simply marketed under the company selling them, while the manufacturer is an entirely different company. AST is both the manufacturer, and marketing company for the finished product. This means that formulation, encapsulation, and bottling are all done in-house.

Attention to detail is important when manufacturing any dietary supplement – let alone systemic enzymes. Our attention to detail ensures that our customer received a product of utmost effectiveness and purity. When we formulate our enzyme blends, enzyme activity is preserved – an art that only an experienced enzyme company is able to perfect. Since there are thousands of possible blends, it takes an expert with a background in enzymology to distinguish the most effective combination in enzyme synergy. Our goal is to ensure that customers receive the highest quality products with the greatest bioavailability – ensuring that the product is absorbed into the bloodstream and actively exerting benefits within the human body.

Listed below are some of the characteristics that make AST Enzymes superior to other brands:

Enteric coated Serrapeptase and Nattokinase

Other distributors have claimed that enzymes do not require a pH resistant coating in order to reach the bloodstream. It is scientific fact that all enzymes have a pH range for activity. Clinical studies note that enzymes must be enterically coated when used systemically, otherwise they are prone to becoming denatured (or inactive). While most fungal and plant-sourced enzymes do exhibit a fairly broad pH activity range – some bacterial enzymes are less tolerant in low pH ranges. Since we are the manufacturer of our products, we are able to test them for both pH and temperature stability. With the results of our own kinetic studies, we are able to prove that serrapeptase and nattokinase are less tolerant in a low pH (like the environment within the stomach), and we are able to enterically coat them to ensure maximum effectiveness.

Enzyme Stabilization with BPPS®

AST’s Bioactive Protein Peptides System® (BPPS) provides stabilization for the enhancement of enzyme activity.

Developed by Specialty Enzymes and Biotechnologies specifically for enzyme stability, BPPS® was a significant advancement made in the 1990’s – although enzyme stabilization has been used since our manufacturing began in 1957.

Although BPPS® was not trademarked until 2004, it was in use long before. Since pure enzymes are not bioavailable, the BPPS® technology allows the enzyme to be bioavailable and gives it a reasonable shelf-life. Stability and tolerance within both the environment and after consumption are topics that our research and development team are constantly improving. Because we are the actual manufacturer with over 50 years of experience, we are able to make these changes as new research emerges. Marketing companies, on the other hand, have less understanding of physio-chemical and kinetic properties of enzymes, and are unable to constantly improve the product.

Assured Quality Enzyme Manufacturing

After the announcement of a voluntary recall of a serrapeptase product sold as Dasen® or Danzen – many of our customers have been concerned about rumors and facts concerning this event. Danzen is produced by Takeda Pharmaceuticals Company Limited and has been sold and distributed by Takeda for nearly 40 years. Many systemic enzyme formulations on the market today contain this product.

According to Takeda reports, The Ministry of Health, Labour and Welfare of Japan requested that additional studies confirm the efficacy of their serrapeptase product after clinical studies failed to show a statistically significant reduction in inflammation with its use. Without further clinical studies to prove their product’s efficacy, they would no longer be allowed to sell it in Japan.

Although Takeda believed in their serrapeptase product, they decided against costly clinical testing and recalled the product instead.

The recall of Takeda’s serrapeptase does not affect the production or sales of AST Enzyme products, as serrapeptase products differ with each manufacturer based on efficacy, coating, activity, bioavailablity, etc.

A member of SEB Group, AST Enzymes is part of a vertically integrated group of companies manufacturing nutraceutical and industrial enzymes. Raw materials like serrapeptase are manufactured in India – the birthplace of our company and center of the enzyme industry. SEB Group is currently the largest manufacturer of serrapeptase worldwide.


With our 5 large-scale manufacturing facilities, all of our in-house labs and testing sites work together to guarantee the same level of activity in every batch of enzymes we produce. Our state of the art ISO 9001:2008 certified manufacturing facilities utilize the most advanced surface and submerged fermentation technologies available.


Vitalzym vs Exclzyme Brand Comparison

Compare Brands Vitalzym vs Neprinol

AST Enzymes has a great research staff that continues to develop new products benefiting ultimately the consumer. Utilizing more than 50 years manufacturing experience, AST Enzymes provides quality and innovation in enzyme products for health care professionals and consumers alike.

We agree that an informed choice is the best choice. Buy Exclzyme today.

Click Exclzyme vs Vitalzym to view a downloadable version of this information.


BPPS® is a registered trademark of Specialty Enzymes and Biotechnologies.
Dasen® is a registered trademark of Takeda Pharmaceuticals Company Limited, which is not affiliated with, nor sponsors or endorses this product or any other product from Specialty Enzymes & Biotechnologies and AST Enzymes.
Vitalzym® is a registered trademark of World Nutrition Inc., which is not affiliated with, nor sponsors or endorses this product or any other product from Specialty Enzymes & Biotechnologies and AST Enzymes.
You can see Takeda’s formal announcement here.

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